And this mutation actually is what saved our species, because if we didnt have the ability to go to a cold place like Europe and get fat in the fall by eating all of the fructose-rich berries, we wouldnt have survived the winters. And by listening to this guy talk about subjects where I have a different point of view, hes sharpening my point of view and sometimes changing my point of view. Peter Attia is the host of The Drive podcast and is a world e. I am absolutely in the process of rewriting it, and that is my intention. ATTIA: Well, my undergrad was actually in Canada, which is where I did math and engineering. His practice focuses on the applied science of longevity. ABOUT DR. PETER ATTIA. Or that we overeat? You remember what Im talking about? So theres this molecule called adenosine. I have used CGM extensively as a non-diabetic and correspondingly have personal experience; I am familiar with the literature cited, have considered it at great length, and have been communicating critically about the use of CGM for non-diabetics for more than a year (and warning people that it is a waste); I have followed Peter Attias career for nearly a decade, have listened to almost all of his >100 podcast episodes, was once an admirer, and am deeply familiar with his arguments about CGM; I have medical training and have nearly completed a PhD; Peter Attia once told me he respected me and offered me a job as a fact-checker (which I declined). In 2014, Attia founded Attia Medical, PC, a medical practice focusing on the applied science of longevity and optimal performance. He is the host of The Drive, one of the most popular podcasts covering the topics of health and medicine. Where did this drive come from? And we do that a ton. Here we fans discuss the cutting edge of longevity science, the latest episodes, and anything we'd like to see/feedback for the future of the podcast. If you learned something today, please share it with us! And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. Dr. Peter Attia. Non-lame, weekly emails on thelatest strategies and tacticsfor increasing your lifespan, healthspan, and well-being (plus new podcast announcements). So lets say youre someone whos only going to get five and a half hours of sleep at night, which for virtually everyone is still suboptimal. I know Im inspired to increase my healthspan in addition to my lifespan, and I hope you are too! Dr. Peter says there are four main ways to do it. Im afraid that I havent done a great job. And then youd just be guaranteed to get N.S.F. Dr. Peter Attia and Dr. Andrew Huberman discuss the truth about dietary cholesterol and what impacts it.Dr. I rarely have a conversation with Peter in which he doesnt introduce me to something Ive never thought about before. And they mightve spent the last 20 of those years in an unbelievable state of misery. Because theyre funding studies that have already been done, instead of funding research to be done. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. If you want bread, eat the bread that has no sugar. I would run between five and 13 miles each morning. But we just have to know what were doing it for and what matters. We finished the round. And these days I spend virtually no time in nutritional ketosis. And I came across this Noam Chomsky documentary. And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. Thanks for listening. Yesterday, I just finished a three-day fast. Lets watch this thing instead. And shes like, Who is this guy? And I said, Look, I dont agree with half the things this guy says, but he is categorically one of the smartest dudes ever. You sometimes need that distance from something. So I just generally say try not to eat too much before bed. Part 1. Peter Attia is a physician focusing on the applied science of longevity. Fish Oil. Post a screenshot of the episode along with your biggest takeaways on Instagram, and make sure to tag Dr. Peter, Stay tuned for Wednesdays episode Part 2 of my interview with Dr. Peter Attia! Additionally, Dr. Peter is an advisor to and/or investor in the following companies: Dr. Peter has an impressive career, but hes an even more impressive person in real life! He attended Stanford University School of Medicine, where he received his M.D. LEVITT: Thats intense. LEVITT: Yeah, I mean, youve listed a bunch of things that we would want to know the answers to that we dont know the answers to. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. He spent two years at the National Institutes of Health as a surgical oncology fellow at the National Cancer Institute, where his research focused on immune-based therapies for melanoma. Born: 1973. And I now realize in retrospect that was almost assuredly primarily being contributed by the lack of sleep. So my hours from 11:00 at night until like 5:00 in the morning, in a cold apartment. Theres days I guess I am. I mean, there is, to me, no upside in outliving everyone that matters to you. And youll tell me your latest thing. And I am so humbled by how bad I am now. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? ATTIA: This is actually something thats really interesting. I dont know if you remember the first time we met, but we were at dinner and it must have been just after your birthday because you were glowing and you said, Oh my God, I got the best birthday present ever from my wife. And just to jog your memory, shed given you some kind of equipment that allowed you to prick your finger and do blood tests. Comments requesting medical advice will not be responded to, as I am not legally permitted to practice medicine over the internet. LEVITT: One of the things that really bothers me about myself is that I can fall asleep anywhere, anytime. Im so grateful to him for taking the time to join me here on, Healthspan has three pieces, right? is directly causal in disease in nondiabetics; There have been no RCTs demonstrating that better glycemic control in nondiabetics leads to better outcomes, much less using CGM; There have not been any long-term studies using CGM in nondiabetics whatsoever; Some of the interventions to reduce CGM readings (say, carbohydrate restriction) also would increase postprandial triglycerides, also associated with worse outcomes; There is therefore an unclear tradeoff between hyperglycemia and hypertriglyceridemia, and that is assuming that they are each causal for bad outcomes in healthy nondiabetics; The cutoffs for unacceptable glucose excursions by Peter Attia are not based on any evidence whatsoever and are arbitrary. ATTIA: So ketosis is arguably one of the most important, if not the most important, metabolic adaptation that allowed our species to survive, because our brains are so dependent on glucose. So, the other night, Olivias like, Daddy, lets watch a movie. And were like, all right. Throughout our lives, we experience different stressors that can cause strain on our mental health. Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. So, Ive done a lot of different things and that makes me a master of nothing. ATTIA: Well, rigidity of thinking is generally a bad thing. Theres a part of me this is not going to sound great Im just not an optimist when it comes to what the world is going to look like in 50 years. I think once I was in medical school and I decided I wanted to become a surgeon, I just had this anxiety, which was, Well, what if you have to operate in the middle of the night and youre tired? So one of the things I started doing in my last year of medical school was, every Thursday night I would stay up, pull an all-nighter, stand at my desk, not allow myself to pee, and practice suturing on my desk in this model that I made that was supposed to resemble a human heart. And thats important, but just as important is our mental health. Right? But the point is, without making these proactive changes, they mightve lived only until 70. Youll have to wait until Wednesday for Dr. Peters definition of greatness, so for now, Ill leave you with one final piece of wisdom: There are people out there who have so many genetic things working against them, that theyll be lucky to make it to 80. And it was very uncomfortable. And then take a little step further, and you reach neurodegenerative disease, of which Alzheimers disease is far and away the most common and also the most rapidly increasing. To listen ad-free, subscribe to Stitcher Premium. So I just generally say try not to eat too much before bed. Peter Attia, MD, is the President and co-Founder of the Nutrition Science Initiative (NuSI). What does it do for you metabolically? Dr. Peters goal is to reduce those early deaths as much as possible. Below this, it has no benefit, above this, its toxic. Dr. Peter focuses on the applied science of longevity, the extension of human life, and overall well-being. Its also that it has no fiber left in it as well. How long? Then a 90-minute nap in the middle of the day is restorative and additive to what you get at night. Peter Attia talks with Steve Levitt about the problem with immortality, what's missing from our Covid response, and why nicotine is underrated. ATTIA: I dont know. Theres days when I really feel like Im getting left behind and the train is so far ahead and Im never going to catch up. ATTIA: I mean, I was a pretty good fighter at the time, but we have a heavy bag in our garage now. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. Its easy to be an armchair quarterback, but its still hard for me to realize why we didnt make a greater effort to ramp up testing quicker. I want to be able to hop over a three-foot fence. Its not about exercising more, especially as he gets older. Ive been enjoying them very much, If you want to know how to live longer, and how to live better, you should be listening to Peter. is part of the Freakonomics Radio Network, and is produced by, and Stitcher. If you learned something today, please share it with us! A surgeon who developed metabolic syndrome himself despite the fact that he ate well and exercised often, Attia realized that our understanding of these important health issues may not actually be correct. Ive known Peter for 10 years. Im actually going to tuck them underneath my lip like chewing tobacco and let it just ease out and keep me going.. And when I was applying for my first grant, I went to the senior people around the M.I.T. But theyre not really set up to do big, big thinking. In addition to being an accomplished physician, Dr. Peter is also a successful businessman. document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Copyright 20122023 PA IP, LLC. And I want you to interrupt me every time you have a question.. into a difficult position, which is to make very incremental steps in science. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. And so, to answer your question, Steve, I am still incredibly bearish on sugar. Have any hacks how to do? for Dr. Peters definition of greatness, so for now, Ill leave you with one final piece of wisdom: There are people out there who have so many genetic things working against them, that theyll be lucky to make it to 80. To me the more important question, Steve, and the one I spend more time thinking about, is: what do you do next time around? Dr. Peter Attia is a medical doctor specializing in health, longevity and preventive medicine. Theres days when I think technologys going to solve all of our problems. Kudos to @SnoozyWeiss. The problem is that we may be living longer, but were living with chronic health conditions that significantly lower our quality of life. So the other thing we always want to be optimizing around is how much fiber can you get? And the more I learned, frankly, the less I agreed with him. . I think its worth understanding that a little bit. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. , Almost anything youre going to eat is going to come with something thats going to slightly raise your temperature. The four huge factors of Type 2 Diabetes. Enjoy this content? Maybe it was partly the placebo effect of all your happy stories about it. And honestly, one of the least predictable and most intelligent people Ive ever met. One half of all Americans are on that spectrum. Dr. Peter Attia. They have to basically show every year that theres an R.O.I. Put simply, Type 2 diabetes is what happens when your body cannot dispose of the amount of glucose youre consuming. Dr. Attia is a huge proponent of supplementing with magnesium. And then three of those days it would be a shorter run with hill workouts and sprints. Airplane versus subway? But something inside said, You dont feel right. So I said, Hey, Mike, I got to call it a day, man. And when I went down to cool down by hitting the speed bag, which is that tiny little round bag that basically has no weight or impact just the impact of hitting that hurt my head so much that I was like, I got to stop.. Why is he telling us this? Whats important about that is the fructose molecule. Which is: what are those people who cant quit also incapable of doing on a day to day basis, vis vis their very rigid view of, this is the way to do things versus not. And Im still generally a somewhat rigid person. Dr. Peter trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year. Hes spent the last few years being mentored by the top medical scientists and now hosts The Drive, a weekly, deep-dive podcast focusing on maximizing longevity by working on physical, cognitive, and emotional health. Its the cognitive piece so how well does your brain work as you age? LEVITT: But when you say risk, you talk about risk of wasting the money? Incredible evidence in how it prevents neurodegeneration and basically all forms of chronic disease. Undergrad was actually in Canada, which is the host of the things that really bothers me about is... 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