dichlorphenamide, lorazepam. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)lorazepam increases and dextroamphetamine decreases sedation. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. ER -, Your free 1 year of online access expired. promethazine and lorazepam both increase sedation. Crit Care Med. Monitor Closely (1)lorazepam and thiothixene both increase sedation. 0000055702 00000 n
Either increases effects of the other by sedation. This information is not individual medical advice and does not substitute for the advice of your health care professional. Bellantuono C, Tofani S, Di Sciascio G, et al. stiripentol, lorazepam. Monitor Closely (1)lorazepam and benperidol both increase sedation. Enter your username below and we'll send you an email explaining how to change your password. Use Caution/Monitor. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)lorazepam increases and armodafinil decreases sedation. lorazepam and pholcodine both increase sedation. Use Caution/Monitor. Effect of interaction is not clear, use caution. Cannabidiol may potentially inhibit UGT2B7 activity. Supplemental digital content is available for this article. Biotin supplementation may be necessary. Coadministration may result in profound sedation, respiratory depression, coma, and/or death. S;~.>J;UKF.3`:3YAz Monitor Closely (1)lorazepam increases and caffeine decreases sedation. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Effect of interaction is not clear, use caution. xref
lorazepam and olanzapine both increase sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.lorazepam, loxapine inhaled. Modify Therapy/Monitor Closely. Monitor Closely (1)lorazepam increases and benzphetamine decreases sedation. Monitor Closely (1)lorazepam and perphenazine both increase sedation. Your dose may need to be gradually decreased.When this medication is used for a long time, it may not work as well. cinnarizine and lorazepam both increase sedation. Offidani E, Guidi J, Tomba E, et al. lorazepam and lormetazepam both increase sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Do not share this medication with others. Modify Therapy/Monitor Closely. Monitor Closely (1)cenobamate, lorazepam. Use Caution/Monitor. 1998 May;26(5):947-56. doi: 10.1097/00003246-199805000-00034. Either increases effects of the other by sedation. Effect of interaction is not clear, use caution. Webdocumenting the conversion using the IV to PO conversion category. Use Caution/Monitor. Dosage adjustment may be necessary if lemborexant is coadministered with other CNS depressants because of potentially additive effects. Download the Johns Hopkins Guides app by Unbound Medicine, 2. depression, hypotension. A 55-bed, mixed-medical, noncardiac surgical PICU in a tertiary care childrens hospital. Use Caution/Monitor. -L Monitor closely for signs of respiratory depression and sedation. Lasmiditan may cause sedation, as well as other cognitive and/or neuropsychiatric adverse reactions. Monitor closely for signs of respiratory depression and sedation. Symptoms of overdose may include confusion, slow reflexes, clumsiness, deep sleep, and loss of consciousness. Monitor Closely (1)perampanel and lorazepam both increase sedation. Sharing it is against the law.Lab and/or medical tests (such as blood counts, liver function) should be done while you are taking this medication. Use Caution/Monitor. Maintenance: 900-1800 mg/day administered in 3 divided doses; doses of up to 2400 mg/day have been tolerated in long-term clinical studies; up to 3600 mg/day has been tolerated in short-term studies. ofloxacin increases levels of lorazepam by decreasing metabolism. Use Caution/Monitor. selinexor, lorazepam. lorazepam and haloperidol both increase sedation. Minor/Significance Unknown. e-N;CM_[9,jPUO'@O%W]I,7wO;~ -O{GOiZb]]qJy=q4/I3>1&p#!EoA2hF"H kn.u,yQg If necessary, adjust dose of alprazolam as needed, Monitor levels of digoxin, and reduce dose as needed, Adjust dose of diazepam as needed, or change to a benzodiazepine eliminated by glucuronidation, Reduce starting dose of alprazolam by 50%; adjust dose further as needed, Alprazolam, diazepam Fosamprenavir (Lexiva), Chlordiazepoxide, clonazepam ketoconazole, Diazepam, lorazepam olanzapine (Zyprexa), Increased risk of cardiorespiratory depression, Avoid use of parenteral benzodiazepines and IM olanzapine, Diazepam phenyton (Dilantin), fosphenytoin (Cerebyx), Monitor phenytoin levels, and adjust dose as needed, Reduce lorazepam starting dose by 50%; adjust dose further as needed, Alprazolam, clonazepam, diazepam ritonavir (Norvir), Alprazolam, diazepam saquinavir (Invirase), Increased sedative/CNS depressant effects, Monitor for sedative effects, and adjust dose of one or both as needed, Monitor for increased sedative/CNS depressant effects, Start tapentadol at 1/3 to 1/2 the usual starting dose. prescription products. Monitor Closely (1)difelikefalin and lorazepam both increase sedation. National Library of Medicine Risk of convulsions. Use Caution/Monitor. lasmiditan, lorazepam. Effect of interaction is not clear, use caution. Minor (1)lorazepam decreases levels of acetaminophen by increasing metabolism. WebSedative-analgesic medications in critically ill adults: Properties, dose regimens, and adverse effects. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Adding plans allows you to compare formulary status to other drugs in the same class. Monitor Closely (1)lorazepam increases and phenylephrine decreases sedation. ewJ;1pRO&+ carbinoxamine and lorazepam both increase sedation. The .gov means its official. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (1)cinnarizine and lorazepam both increase sedation. The risk of dependence is increased with the agents that are rapidly absorbed and with shorter half-lives, i.e., alprazolam and diazepam. Use Caution/Monitor. Monitor Closely (1)lorazepam and doxylamine both increase sedation. Monitor Closely (1)lorazepam and mirtazapine both increase sedation. The dosage of a benzodiazepine will vary depending on the patient and his or her history of sedative use. primidone and lorazepam both increase sedation. lorazepam and chlorzoxazone both increase sedation. Use Caution/Monitor. Monitor Closely (1)secobarbital and lorazepam both increase sedation. Use Caution/Monitor. Wolters Kluwer Health
Modify Therapy/Monitor Closely. Minor (1)lorazepam decreases effects of succinylcholine by pharmacodynamic antagonism. Monitor Closely (1)lorazepam and triclofos both increase sedation. Use Caution/Monitor. Monitor Closely (1)lorazepam and daridorexant both increase sedation. orlistat decreases levels of lorazepam by inhibition of GI absorption. 0000008055 00000 n
. WebPeak plasma levels were reached at 1.15 hr after dosage, with absorption half-life averaging 14.2 (+/- 4.7) min. hydrocodone, lorazepam. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. 0000004027 00000 n
Monitor Closely (1)diphenhydramine and lorazepam both increase sedation. estazolam and lorazepam both increase sedation. Use Caution/Monitor. lorazepam and olopatadine intranasal both increase sedation. Use Caution/Monitor. lorazepam and loxapine both increase sedation. Use Caution/Monitor. Monitor Closely (1)lorazepam increases and arformoterol decreases sedation. etomidate and lorazepam both increase sedation. Use Caution/Monitor. Monitor Closely (1)dimenhydrinate and lorazepam both increase sedation. Monitor Closely (1)lorazepam and lofepramine both increase sedation. lorazepam and clozapine both increase sedation. lemborexant, lorazepam. brexanolone, lorazepam. lorazepam decreases levels of acetaminophen rectal by increasing metabolism. Minor/Significance Unknown. Monitor Closely (1)triprolidine and lorazepam both increase sedation. Well, the benzodiazepine conversion calculator has got your back! levofloxacin increases levels of lorazepam by decreasing metabolism. chlorpheniramine and lorazepam both increase sedation. Talk to your doctor if you are using marijuana (cannabis).Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. Use Caution/Monitor. Use Caution/Monitor. clorazepate and lorazepam both increase sedation. Avoid or Use Alternate Drug. Use Caution/Monitor. x]r}g*~qXE-GmqyHJbBr^|c],^ @r\4Plxy+XNr^X/ Use Caution/Monitor. Lorazepam belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. Avoid or Use Alternate Drug. Monitor Closely (1)chlorpheniramine and lorazepam both increase sedation. Use Caution/Monitor. Monitor Closely (1)lorazepam and ramelteon both increase sedation. Monitor Closely (1)sevoflurane and lorazepam both increase sedation. Consult your pharmacist or local waste disposal company. Monitor Closely (1)lorazepam increases and epinephrine racemic decreases sedation. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.This drug passes into breast milk. Monitor Closely (1)lorazepam and dextromoramide both increase sedation. If a benzodiazepine must be used for an indication other than seizures, lower the benzodiazepine initial dose and cautiously titrate to clinical response. lorazepam and dextromoramide both increase sedation. Use Caution/Monitor. Effect of interaction is not clear, use caution. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Use Caution/Monitor. Minor (1)lorazepam, pyrimethamine. An intramuscular dose (not available in the U.S.) of 50-100 mg can be given every 4 hours if needed for alcohol withdrawal. Coadministration of CNS depressants can result in serious, life-threatening, and fatal respiratory depression. Either increases toxicity of the other by pharmacodynamic synergism. in comparison to barbiturates, they are: Benzodiazepines are not the only drugs used for anxiety we usually start our treatment with medicines such as Benadryl, that have a milder effect and are not as addictive as benzodiazepines. 0000001412 00000 n
Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. lorazepam and triazolam both increase sedation. Minor (1)lorazepam decreases levels of cyanocobalamin by inhibition of GI absorption. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. diphenhydramine and lorazepam both increase sedation. Clonazepam (Klonopin): The initial dose is 0.25 mg daily to twice a day; the dose can be increased by 0.125-0.25 mg daily or two times a day every 2-3 days; the usual therapeutic dose is 1-4 mg total/day in divided doses. cont. Use Caution/Monitor. 0000001594 00000 n
WebNot technically IV = PO but if pt. Use Caution/Monitor. lorazepam and protriptyline both increase sedation. 0000006132 00000 n
Modify Therapy/Monitor Closely. Either increases effects of the other by pharmacodynamic synergism. One may preferably choose lorazepam or oxazepam: both are metabolized through conjugation and do not produce active metabolites (fewer CYP 450 drug interactions). This drug is available at a middle level co-pay. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Use Caution/Monitor. lorazepam and buprenorphine buccal both increase sedation. Use Caution/Monitor. Monitor Closely (1)cannabidiol will increase the level or effect of lorazepam by decreasing metabolism. lorazepam increases and phendimetrazine decreases sedation. Minor/Significance Unknown. Monitor Closely (1)etomidate and lorazepam both increase sedation. Either increases effects of the other by sedation. Use Caution/Monitor. lorazepam and fluphenazine both increase sedation. Call your doctor to find out what to do. lorazepam and cyclobenzaprine both increase sedation. Monitor Closely (1)lorazepam and chlorzoxazone both increase sedation. Minor/Significance Unknown. Use Caution/Monitor. Avoid or Use Alternate Drug. H\TKoAqs;O Some error has occurred while processing your request. Coadministration may potentiate the CNS-depressant effects of each drug. Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. Use Caution/Monitor. lorazepam and moxonidine both increase sedation. Coadministration of buprenorphine and The benzodiazepine conversion calculator is an ultimate solution to any dosage problems you might encounter while switching from one drug of this type to another. 0000007240 00000 n
T1 - Benzodiazepines Use Caution/Monitor. benzodiazepine use may lead to clinically significant physical dependence; risk of dependence and withdrawal incr. suvorexant and lorazepam both increase sedation. Comment: Drug combination has been found to be incompatible. Monitor Closely (1)lorazepam and levorphanol both increase sedation. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvYXRpdmFuLWxvcmVldi14ci1sb3JhemVwYW0tMzQyOTA2, View explanations for tiers and lorazepam and ramelteon both increase sedation. 0000063370 00000 n
Use Caution/Monitor. Minor/Significance Unknown. WARNING: Lorazepam has a risk for abuse and addiction, which can lead to overdose and death. *Ovv]pu}gz$3 lorazepam and methadone both increase sedation. 0000003285 00000 n
Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Monitor Closely (1)lorazepam increases and propylhexedrine decreases sedation. Monitor Closely (1)chlordiazepoxide and lorazepam both increase sedation. Use Caution/Monitor. Copyright(c) 2023 First Databank, Inc. Coadministration may result in profound sedation, respiratory depression, coma, and/or death. official website and that any information you provide is encrypted Minor (1)lorazepam decreases effects of vecuronium by pharmacodynamic antagonism. Consider reducing the dose when concomitantly using UGT2B7 substrates.
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Coadministration of CNS depressants can result in serious, life-threatening, and fatal respiratory depression. Use Caution/Monitor. Patients: amobarbital and lorazepam both increase sedation. WebAntipsychotics for initial management of the acutely agitated adult patient with psychosis. Use Caution/Monitor. Profound sedation, respiratory depression, coma, and death may result if coadministered. lorazepam and amitriptyline both increase sedation. Use Caution/Monitor. Modify Therapy/Monitor Closely. Either increases effects of the other by sedation. Use Caution/Monitor. Monitor Closely (1)ketamine and lorazepam both increase sedation. 0000004769 00000 n
Use Caution/Monitor. A double-blind, randomized comparison of i.v. RN2NpN )lbV 3: (KF 0000010283 00000 n
Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor Closely (1)lorazepam and buprenorphine both increase sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown. Monitor Closely (1)suvorexant and lorazepam both increase sedation. Either increases toxicity of the other by pharmacodynamic synergism. Weblorazepam increases toxicity of buprenorphine, long-acting injection by pharmacodynamic synergism. Monitor Closely (1)clorazepate and lorazepam both increase sedation. butabarbital and lorazepam both increase sedation. lorazepam increases and terbutaline decreases sedation. Limit dosages and durations to the minimum required. Monitor Closely (1)brexanolone, lorazepam. Minor/Significance Unknown. Minor/Significance Unknown. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, glaucoma, lung/breathing problems (such as sleep apnea), mental/mood disorders (such as depression, psychosis), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol).This drug may make you dizzy or drowsy or blur your vision. lorazepam increases and lisdexamfetamine decreases sedation. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. lorazepam and prochlorperazine both increase sedation. Use Caution/Monitor. Anticonvulsant: Oral: Initial: 300 mg 3 times/day, if necessary the dose may be increased up to 1800 mg/day. lorazepam and maprotiline both increase sedation. depression, hypotension. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. alprazolam and lorazepam both increase sedation. Monitor Closely (1)lorazepam and trazodone both increase sedation. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS).
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